•Application page
Application page is an a template page from _layouts virtual directory with following characteristics: –it is available within every site –only one copy of this page on the server –It is not accessible through Designer when editing a site –It is accessible through IIS
•Safe page
Safe page is a template page that comes from site definitions (For example: default.aspx in "Team Site" template). –it exists only on sites where it's been specified by a template or created by a user –many copies can exist on the server –It is accessible through Designer when editing a site –It is not accessible through IIS
